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5-Chloro-2,4-difluorobenzenesulfonyl chloride

5-Chloro-2,4-difluorobenzenesulfonyl chloride (CAS 13656-57-0) is a high-purity fluorinated benzene sulfonyl chloride intermediate widely used in pharmaceutical synthesis and organic chemistry research. This compound features both chloro and difluoro substituents on the benzene ring, making it a highly reactive electrophilic reagent for sulfonylation reactions. As a key building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals, it exhibits excellent reactivity in nucleophilic substitution reactions. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for API synthesis, medicinal chemistry research, and industrial applications. This compound is particularly valuable in the development of sulfonamide-based drugs and fluorinated pharmaceutical intermediates.

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Product Name
5-Chloro-2,4-difluorobenzenesulfonyl chloride
CAS Number
13656-57-0
Chinese Name
5-氯-2,4-二氟苯磺酰氯
Synonyms
5-Chloro-2,4-difluorobenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 5-chloro-2,4-difluoro-; 5-Chloro-2,4-difluorobenzenesulfonyl chloride; CDFSC; 2,4-Difluoro-5-chlorobenzenesulfonyl chloride
Chinese Synonyms
5-氯-2,4-二氟苯磺酸氯; 5-氯-2,4-二氟苯-1-磺酰氯
Molecular Formula
C₆H₂Cl₂F₂O₂S
Molecular Weight
243.05 g/mol
Purity
≥ 98%
Product Category
Pharmaceutical Intermediates / Benzene Derivatives / Sulfonyl Chlorides
Appearance
White to off-white crystalline solid
Storage Conditions
Store in a cool, dry, well-ventilated area away from moisture and light. Keep container tightly closed. Moisture sensitive.
Shelf Life
24 months under recommended storage conditions
Packaging
25kg/drum, 50kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, sulfonylation reactions, API synthesis, agrochemical intermediates, sulfonamide drug development
Reactivity
Suitable for sulfonylation reactions, nucleophilic substitution, sulfonamide synthesis