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4-CHLORO-3-NITROBENZYL ALCOHOL

4-Chloro-3-nitrobenzyl alcohol (CAS 55912-20-4) is a high-purity chloro-nitro substituted benzyl alcohol intermediate widely used in pharmaceutical synthesis, organic chemistry research, and fine chemical manufacturing. This compound features a chlorine substituent at the para-position and a nitro group at the meta-position of the benzyl alcohol structure, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in reduction reactions, nucleophilic substitution, and functional group transformations, it exhibits excellent reactivity in catalytic hydrogenation (nitro to amino), esterification, etherification, and cross-coupling pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing chloro-nitro aromatic scaffolds, agrochemical intermediates, and specialty chemical precursors. As a reliable benzene derivative intermediate, it serves as an important precursor for constructing functionalized aromatic systems in drug discovery and fine chemical development programs.

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Product Name
4-Chloro-3-nitrobenzyl alcohol
CAS Number
55912-20-4
Chinese Name
4-氯-3-硝基苯甲醇
Synonyms
(4-Chloro-3-nitrophenyl)methanol; Benzyl alcohol, 4-chloro-3-nitro-; 4-Chloro-3-nitrobenzenemethanol; 3-Nitro-4-chlorobenzyl alcohol; 4-Chloro-m-nitrobenzyl alcohol; 1-(Hydroxymethyl)-4-chloro-3-nitrobenzene; 4-Cl-3-NO₂-benzyl alcohol
Chinese Synonyms
3-硝基-4-氯苯甲醇; 4-氯-3-硝基苄醇; 1-(羟甲基)-4-氯-3-硝基苯; 对氯间硝基苯甲醇
Molecular Formula
C₇H₆ClNO₃
Molecular Weight
187.58 g/mol
Purity
≥ 98% (HPLC)
Product Category
Pharmaceutical Intermediates / Benzene Derivatives / Nitrobenzyl Alcohols
Appearance
Light Yellow to Yellow Crystalline Powder or Solid
Melting Point
95-99°C (estimated)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and reducing agents.
Shelf Life
24 months under recommended storage conditions
Packaging
1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, organic synthesis, API manufacturing, nitro reduction reactions, nucleophilic substitution, esterification, etherification, agrochemical intermediates, fine chemical production
Reactivity
Suitable for catalytic hydrogenation (nitro to amino), esterification, etherification, nucleophilic substitution, oxidation to aldehyde/acid, and chloro-directed ortho-functionalization