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2-(3-Chlorophenoxy)-propionic acid
2-(3-Chlorophenoxy)propionic acid (CAS 101-10-0), commonly known as Cloprop, is a high-purity chlorophenoxy carboxylic acid intermediate widely used in pharmaceutical synthesis, agrochemical development, plant growth regulator manufacturing, and fine chemical production. This compound features a chlorine substituent at the meta-position of the phenoxy group and a propionic acid side chain, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in esterification, amide coupling, and functional group transformations, it exhibits excellent reactivity in nucleophilic substitution, cross-coupling reactions, and derivatization pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, agrochemical formulation, medicinal chemistry research, and scale-up production. This compound is particularly valuable in the synthesis of plant growth regulators, herbicide intermediates, pharmaceuticals containing chlorophenoxy scaffolds, and specialty chemical precursors.
Property
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Product Name
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2-(3-Chlorophenoxy)propionic acid
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CAS Number
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101-10-0
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Chinese Name
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调果酸
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Synonyms
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Cloprop; 2-(3-Chlorophenoxy)propanoic acid; 3-Chlorophenoxypropionic acid; m-Chlorophenoxypropionic acid; α-(3-Chlorophenoxy)propionic acid; 2-(m-Chlorophenoxy)propionic acid; DL-2-(3-Chlorophenoxy)propionic acid; 3-CPA; α-(m-Chlorophenoxy)propionic acid
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Chinese Synonyms
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2-(3-氯苯氧基)丙酸; 间氯苯氧基丙酸; α-(3-氯苯氧基)丙酸; 调果酸; 3-氯苯氧基丙酸; 间氯苯氧基丙酸
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Molecular Formula
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C₉H₉ClO₃
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Molecular Weight
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200.62 g/mol
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Purity
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≥ 98% (HPLC/GC)
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Product Category
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Pharmaceutical Intermediates / Benzene Derivatives / Chlorophenoxy Acids
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Appearance
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White to Off-white Crystalline Powder
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Melting Point
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105-108°C (literature)
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Storage Conditions
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Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and bases.
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Shelf Life
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24 months under recommended storage conditions
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Packaging
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1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
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Applications
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Pharmaceutical intermediates, agrochemical intermediates, plant growth regulator synthesis, herbicide development, esterification reactions, amide coupling, fine chemical production, organic synthesis
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Reactivity
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Suitable for esterification, amide bond formation, nucleophilic substitution, cross-coupling reactions, and chlorophenoxy-directed functionalization
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