(5-Amino-2-chlorophenyl)methanol

(5-Amino-2-chlorophenyl)methanol (CAS 89951-56-4), also known as 5-Amino-2-chlorobenzyl alcohol or 2-Chloro-5-aminobenzyl alcohol, is a high-purity chloro-amino substituted benzyl alcohol intermediate widely used in pharmaceutical synthesis, organic chemistry research, and fine chemical manufacturing. This compound features an amino group at the para-position and a chlorine substituent at the ortho-position of the benzyl alcohol structure, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in nucleophilic substitution, reductive amination, and functional group transformations, it exhibits excellent reactivity in amide coupling, etherification, esterification, and cross-coupling pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing chloro-amino aromatic scaffolds, heterocyclic intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable benzene derivative intermediate from our benzene series product line, it serves as an important precursor for constructing amino-functionalized aromatic systems in drug discovery and fine chemical development programs.

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Product Name	(5-Amino-2-chlorophenyl)methanol
CAS Number	89951-56-4
Chinese Name	5-氨基-2-氯苄基醇
Synonyms	5-Amino-2-chlorobenzyl alcohol; 2-Chloro-5-aminobenzyl alcohol; (2-Chloro-5-aminophenyl)methanol; Benzyl alcohol, 5-amino-2-chloro-; 2-Chloro-5-aminophenylmethanol; 5-Amino-2-chloro-α-hydroxytoluene; 1-(Hydroxymethyl)-4-amino-2-chlorobenzene; 2-Cl-5-NH₂-benzyl alcohol
Chinese Synonyms	5-氨基-2-氯苄醇; 2-氯-5-氨基苯甲醇; 1-(羟甲基)-4-氨基-2-氯苯; 邻氯对氨基苯甲醇; 5-氨基-2-氯-α-羟基甲苯
Molecular Formula	C₇H₈ClNO
Molecular Weight	157.60 g/mol
Purity	≥ 98% (HPLC)
Product Category	Pharmaceutical Intermediates / Benzene Derivatives / Aminobenzyl Alcohols
Appearance	White to Off-white Crystalline Powder or Light Yellow Solid
Melting Point	95-100°C (estimated)
Storage Conditions	Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from oxidation and strong oxidizing agents.
Shelf Life	24 months under recommended storage conditions
Packaging	1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
Applications	Pharmaceutical intermediates, organic synthesis, API manufacturing, nucleophilic substitution, reductive amination, amide coupling, heterocyclic synthesis, agrochemical intermediates, fine chemical production
Reactivity	Suitable for amide bond formation, esterification, etherification, nucleophilic substitution, reductive amination, and amino/chloro-directed ortho-functionalization