1-Chloro-4-(3-chloropropyl)benzene

3-(3-Chlorophenyl)propanoic acid (CAS 64473-34-3), also known as m-Chlorohydrocinnamic acid or 3-(3-Chlorophenyl)propionic acid, is a high-purity chlorinated aromatic carboxylic acid intermediate widely used in pharmaceutical synthesis, organic chemistry research, and fine chemical manufacturing. This compound features a chlorine substituent at the meta-position of the phenyl ring linked to a propanoic acid side chain, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in esterification, amide coupling, and functional group transformations, it exhibits excellent reactivity in Friedel-Crafts acylation, cross-coupling reactions, and derivatization pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing meta-chlorophenyl scaffolds, anti-inflammatory drug intermediates, analgesic precursors, and specialty chemical precursors. As a reliable benzene derivative intermediate from our product line, it serves as an important precursor for constructing functionalized aromatic carboxylic acid systems in drug discovery and fine chemical development programs.

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Product Name	3-(3-Chlorophenyl)propanoic acid
CAS Number	64473-34-3
Chinese Name	3-(3-氯苯基)丙酸
Synonyms	m-Chlorohydrocinnamic acid; 3-(3-Chlorophenyl)propionic acid; Benzenepropanoic acid, 3-chloro-; 3′-Chlorohydrocinnamic acid; 3-(m-Chlorophenyl)propionic acid; 3-Chlorophenylpropionic acid; ClC₆H₄CH₂CH₂CO₂H; meta-Chlorohydrocinnamic acid
Chinese Synonyms	间氯氢化肉桂酸; 3-(间氯苯基)丙酸; 3-氯苯丙酸; 间氯苯基丙酸; 3-氯苯基丙酸; 间氯苯基丙酸
Molecular Formula	C₉H₉ClO₂
Molecular Weight	184.62 g/mol
Purity	≥ 98% (HPLC/GC)
Product Category	Pharmaceutical Intermediates / Benzene Derivatives / Chlorophenyl Carboxylic Acids
Appearance	White to Off-white Crystalline Powder
Melting Point	85-90°C (estimated)
Storage Conditions	Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and bases.
Shelf Life	24 months under recommended storage conditions
Packaging	1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
Applications	Pharmaceutical intermediates, organic synthesis, API manufacturing, anti-inflammatory drug synthesis, analgesic precursors, esterification reactions, amide coupling, agrochemical intermediates, fine chemical production
Reactivity	Suitable for esterification, amide bond formation, Friedel-Crafts reactions, Suzuki coupling, nucleophilic substitution, and meta-chloro-directed functionalization