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4-BENZYLOXYBENZYL ALCOHOL
3-(4-Methoxyphenyl)propanoic acid (CAS 836-43-1), also known as p-Methoxyhydrocinnamic acid or 4-Methoxybenzenepropanoic acid, is a high-purity methoxy-substituted aromatic carboxylic acid intermediate widely used in pharmaceutical synthesis, organic chemistry research, fragrance chemistry, and fine chemical manufacturing. This compound features a methoxy group at the para-position of the phenyl ring linked to a propanoic acid side chain, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in esterification, amide coupling, and functional group transformations, it exhibits excellent reactivity in Friedel-Crafts acylation, cross-coupling reactions, and derivatization pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, fragrance formulation, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing para-methoxyphenyl scaffolds, anti-inflammatory drug intermediates, fragrance precursors, and specialty chemical precursors. As a reliable benzene derivative intermediate from our product line, it serves as an important precursor for constructing functionalized aromatic carboxylic acid systems in drug discovery and fine chemical development programs.
Property
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Product Name
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3-(4-Methoxyphenyl)propanoic acid
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CAS Number
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836-43-1
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Chinese Name
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3-(4-甲氧基苯基)丙酸
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Synonyms
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p-Methoxyhydrocinnamic acid; 4-Methoxybenzenepropanoic acid; Benzenepropanoic acid, 4-methoxy-; 4′-Methoxyhydrocinnamic acid; 3-(p-Methoxyphenyl)propionic acid; 4-Methoxyphenylpropionic acid; MeOC₆H₄CH₂CH₂CO₂H; 4-Methoxyhydrocinnamic acid; Dihydro-p-coumaric acid methyl ether
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Chinese Synonyms
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对甲氧基氢化肉桂酸; 3-(对甲氧基苯基)丙酸; 4-甲氧基苯丙酸; 对甲氧基苯基丙酸; 4-甲氧基苯基丙酸; 对甲氧基氢化肉桂酸
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Molecular Formula
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C₁₀H₁₂O₃
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Molecular Weight
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180.20 g/mol
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Purity
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≥ 98% (HPLC/GC)
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Product Category
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Pharmaceutical Intermediates / Benzene Derivatives / Methoxyphenyl Carboxylic Acids
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Appearance
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White to Off-white Crystalline Powder
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Melting Point
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105-108°C (literature)
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Storage Conditions
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Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and bases.
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Shelf Life
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24 months under recommended storage conditions
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Packaging
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1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
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Applications
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Pharmaceutical intermediates, organic synthesis, API manufacturing, anti-inflammatory drug synthesis, fragrance chemistry, esterification reactions, amide coupling, agrochemical intermediates, fine chemical production
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Reactivity
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Suitable for esterification, amide bond formation, Friedel-Crafts reactions, Suzuki coupling, nucleophilic substitution, and para-methoxy-directed ortho-functionalization
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