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3-Pyridinemethanol
3-Pyridinemethanol (CAS 100-55-0), also known as 3-(Hydroxymethyl)pyridine or Nicotinyl alcohol, is a high-purity hydroxymethyl-substituted pyridine intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features a hydroxymethyl group at the 3-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in oxidation reactions, esterification, etherification, and nucleophilic substitution, it exhibits excellent reactivity in conversion to nicotinaldehyde, nicotinic acid derivatives, and heterocyclic functionalization pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, rodenticide intermediate synthesis (such as norbormide precursors), and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing pyridylmethanol scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.
Property
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Product Name
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3-Pyridinemethanol
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CAS Number
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100-55-0
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Chinese Name
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3-吡啶甲醇
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Synonyms
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3-(Hydroxymethyl)pyridine; Nicotinyl alcohol; ω-Hydroxy-3-picoline; 3-Pyridyl carbinol; Pyridine-3-methanol; C₆H₇NO heterocycle; MFCD00006407
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Chinese Synonyms
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3-(羟甲基)吡啶; 烟酰醇; ω-羟基-3-甲基吡啶; 3-吡啶基甲醇; 吡啶-3-甲醇
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Molecular Formula
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C₆H₇NO
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Molecular Weight
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109.13 g/mol
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Purity
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≥ 98% (GC/HPLC)
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Product Category
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Pharmaceutical Intermediates / Pyridine Derivatives / Hydroxymethylpyridines
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Appearance
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Colorless to Light Yellow Hygroscopic Liquid
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Boiling Point
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~240-245°C at 760 mmHg (estimated)
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Density
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1.124 g/cm³ at 25°C
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Refractive Index
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n₂₀/D ~1.55 (estimated)
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Storage Conditions
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Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen or argon). This compound is highly hygroscopic – protect from moisture. Store at 2-8°C for extended stability.
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Shelf Life
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24 months under recommended storage conditions
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Packaging
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100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
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Applications
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Pharmaceutical intermediates, organic synthesis, API manufacturing, rodenticide synthesis (norbormide precursors), heterocyclic chemistry, oxidation to nicotinaldehyde, esterification, agrochemical intermediates, fine chemical production
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Reactivity
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Suitable for oxidation to aldehyde/acid, esterification, etherification, nucleophilic substitution, and hydroxymethyl group derivatization
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