N-Methyl-4-pyridinamine

4-(Methylamino)pyridine (CAS 1121-58-0), also known as N-Methyl-4-pyridinamine or 4-Methylaminopyridine, is a high-purity methylamino-substituted pyridine intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features a methylamino group (-NHCH₃) at the 4-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in nucleophilic substitution, reductive amination, amide coupling, and heterocyclic functionalization, it exhibits excellent reactivity in electrophilic aromatic substitution, cross-coupling reactions, and nitrogen-directed derivatization pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, kinase inhibitor synthesis, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing 4-aminopyridine scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

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Product Name	4-(Methylamino)pyridine
CAS Number	1121-58-0
Chinese Name	4-甲氨基吡啶
Synonyms	N-Methyl-4-pyridinamine; 4-Methylaminopyridine; Pyridin-4-amine, N-methyl-; N-Methylpyridin-4-amine; C₆H₈N₂ heterocycle;
Chinese Synonyms	N-甲基-4-吡啶胺; 4-甲基氨基吡啶; 吡啶-4-胺,N-甲基-; N-甲基吡啶-4-胺; 甲氨基吡啶
Molecular Formula	C₆H₈N₂
Molecular Weight	108.14 g/mol
Purity	≥ 98% (GC/HPLC)
Product Category	Pharmaceutical Intermediates / Pyridine Derivatives / Methylaminopyridines
Appearance	White to Off-white Crystalline Powder or Solid
Melting Point	55-60°C (estimated)
Boiling Point	~200-205°C at 760 mmHg (estimated)
Density	~1.08 g/cm³ (estimated)
Storage Conditions	Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen or argon). Protect from strong oxidizing agents and acids. Store at 2-8°C for extended stability.
Shelf Life	24 months under recommended storage conditions
Packaging	100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications	Pharmaceutical intermediates, organic synthesis, API manufacturing, kinase inhibitor synthesis, heterocyclic chemistry, nucleophilic substitution, reductive amination, amide coupling, agrochemical intermediates, fine chemical production
Reactivity	Suitable for electrophilic aromatic substitution, nucleophilic substitution, reductive amination, amide bond formation, cross-coupling reactions, and methylamino group derivatization