purines and pyrimidines​manufacture​supplier|Wealsun Biotech https://wealsunbio.com/product-category/pyrimidines/ Sat, 28 Feb 2026 02:06:55 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://wealsunbio.com/wp-content/uploads/2025/06/20260211161228_5028_5-e1770797653670.png purines and pyrimidines​manufacture​supplier|Wealsun Biotech https://wealsunbio.com/product-category/pyrimidines/ 32 32 3-Bromo-4-methyl-5-nitropyridine https://wealsunbio.com/product/3-bromo-4-methyl-5-nitropyridine/ https://wealsunbio.com/product/3-bromo-4-methyl-5-nitropyridine/#respond Sat, 24 Jan 2026 12:43:49 +0000 https://wealsunbio.com/?post_type=product&p=22308 3-Bromo-4-methyl-5-nitropyridine (CAS 69872-15-7) is a strategically tri-substituted pyridine scaffold engineered for regioselective diversification in medicinal chemistry and agrochemical R&D. Featuring bromine at C3, methyl at C4, and nitro at C5, this polyfunctionalized heterocycle enables orthogonal synthetic manipulation: the C3-bromo substituent serves as a privileged handle for Pd-catalyzed cross-coupling (Suzuki, Buchwald-Hartwig, Sonogashira), while the C5-nitro group offers a reducible motif to access amino-pyridine pharmacophores, and the C4-methyl group provides steric and electronic tuning for target binding optimization. This intermediate is particularly valuable for constructing kinase inhibitor cores, neonicotinoid analogs, and heterocyclic APIs where precise 3,4,5-trisubstitution patterns modulate biological activity. Manufactured with purity ≥98% under stringent QC protocols, it supports scalable routes to complex pyridine-based therapeutics requiring meta/para-disubstituted aromatic architectures.

The post 3-Bromo-4-methyl-5-nitropyridine appeared first on wealsunbio.

]]>
Product Name
3-Bromo-4-methyl-5-nitropyridine
CAS Number
69872-15-7
Chinese Name
3-溴-4-甲基-5-硝基吡啶
Synonyms
3-Bromo-4-methyl-5-nitro-1-azabenzene; Pyridine, 3-bromo-4-methyl-5-nitro-; 3-Bromo-5-nitro-4-picoline; C₆H₅BrN₂O₂ heterocycle; MFCD11847767
Chinese Synonyms
3-溴-4-甲基-5-硝基-1-氮杂苯; 3-溴-5-硝基-4-甲基吡啶; 溴甲基硝基吡啶; 3-溴-4-甲基-5-硝基吡啶
Molecular Formula
C₆H₅BrN₂O₂
Molecular Weight
217.02 g/mol
Purity
≥ 98% (GC/HPLC)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Polyfunctionalized Nitropyridines
Appearance
Yellow to Brown Crystalline Powder or Solid
Melting Point
57-58°C (literature)
Boiling Point
~320°C at 760 mmHg (estimated)
Density
~1.75 g/cm³ (estimated)
Flash Point
116.3±25.9°C
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen). Protect from strong reducing agents to prevent premature nitro reduction.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Kinase inhibitor synthesis, neonicotinoid agrochemical development, regioselective pyridine functionalization, nitro reduction to amino, C3-selective cross-coupling, methyl group C–H functionalization strategies
Reactivity
Suitable for Suzuki coupling, Buchwald-Hartwig amination, Sonogashira coupling (preferential C3-Br displacement), catalytic hydrogenation (nitro to amino), electrophilic aromatic substitution at C6, and methyl group oxidation/functionalization
Special Note
✅ Light-sensitive solid with orthogonal reactivity—C3-Br for coupling, C5-NO₂ for reduction, C4-Me for steric modulation. Part of our pyridine derivative series.

The post 3-Bromo-4-methyl-5-nitropyridine appeared first on wealsunbio.

]]> https://wealsunbio.com/product/3-bromo-4-methyl-5-nitropyridine/feed/ 0 4-Hydroxy-3-nitropyridine https://wealsunbio.com/product/4-hydroxy-3-nitropyridine/ https://wealsunbio.com/product/4-hydroxy-3-nitropyridine/#respond Sat, 24 Jan 2026 12:43:23 +0000 https://wealsunbio.com/?post_type=product&p=22307 4-Hydroxy-3-nitropyridine (CAS 5435-54-1), also known as 3-Nitropyridin-4-ol or 3-Nitro-4-pyridinol, is a high-purity hydroxy-nitro substituted pyridine intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features a hydroxyl group at the 4-position and a nitro group at the 3-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in nucleophilic aromatic substitution, nitro group reduction, and hydroxyl group derivatization, it exhibits excellent reactivity in catalytic hydrogenation, etherification, esterification, and heterocyclic functionalization pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, kinase inhibitor synthesis, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing hydroxynitropyridine scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

The post 4-Hydroxy-3-nitropyridine appeared first on wealsunbio.

]]>
Product Name
4-Hydroxy-3-nitropyridine
CAS Number
5435-54-1
Chinese Name
4-羟基-3-硝基吡啶
Synonyms
3-Nitropyridin-4-ol; 3-Nitro-4-pyridinol; Pyridin-4-ol, 3-nitro-; 3-Nitro-4-hydroxypyridine; C₅H₄N₂O₃ heterocycle; MFCD00128874
Chinese Synonyms
3-硝基吡啶-4-醇; 3-硝基-4-羟基吡啶; 4-羟基-3-硝基吡啶; 硝基羟基吡啶
Molecular Formula
C₅H₄N₂O₃
Molecular Weight
140.10 g/mol
Purity
≥ 98% (HPLC/GC)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Hydroxynitropyridines
Appearance
Yellow to Brown Crystalline Powder or Solid
Melting Point
285°C (decomposition, literature)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and reducing agents. Store sealed at 2-8°C for extended stability.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, organic synthesis, API manufacturing, kinase inhibitor synthesis, heterocyclic chemistry, nitro reduction to amino, hydroxyl group derivatization, agrochemical intermediates, fine chemical production
Reactivity
Suitable for catalytic hydrogenation (nitro to amino), nucleophilic aromatic substitution, hydroxyl group etherification/esterification, electrophilic aromatic substitution, and heterocyclic ring functionalization

The post 4-Hydroxy-3-nitropyridine appeared first on wealsunbio.

]]> https://wealsunbio.com/product/4-hydroxy-3-nitropyridine/feed/ 0 3-Bromo-4-hydroxy-5-nitropyridine https://wealsunbio.com/product/3-bromo-4-hydroxy-5-nitropyridine/ https://wealsunbio.com/product/3-bromo-4-hydroxy-5-nitropyridine/#respond Sat, 24 Jan 2026 12:43:02 +0000 https://wealsunbio.com/?post_type=product&p=22306 3-Bromo-4-hydroxy-5-nitropyridine (CAS 31872-65-8), also known as 3-Bromo-5-nitropyridin-4-ol or Pyridine, 3-bromo-4-hydroxy-5-nitro-, is a high-purity bromo-hydroxy-nitro substituted pyridine intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features a bromine substituent at the 3-position, a hydroxyl group at the 4-position, and a nitro group at the 5-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in cross-coupling reactions, nucleophilic aromatic substitution, nitro group reduction, and hydroxyl group derivatization, it exhibits excellent reactivity in Suzuki coupling, Buchwald-Hartwig amination, catalytic hydrogenation, and selective bromine displacement pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, kinase inhibitor synthesis, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing polyfunctionalized pyridine scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

The post 3-Bromo-4-hydroxy-5-nitropyridine appeared first on wealsunbio.

]]>
Product Name
3-Bromo-4-hydroxy-5-nitropyridine
CAS Number
31872-65-8
Chinese Name
3-溴-4-羟基-5-硝基吡啶
Synonyms
3-Bromo-5-nitropyridin-4-ol; Pyridine, 3-bromo-4-hydroxy-5-nitro-; 3-Bromo-4-hydroxy-5-nitro-1-azabenzene; C₅H₃BrN₂O₃ heterocycle; MFCD08692339
Chinese Synonyms
3-溴-5-硝基吡啶-4-醇; 3-溴-4-羟基-5-硝基-1-氮杂苯; 溴羟基硝基吡啶; 3-溴-4-羟基-5-硝基吡啶
Molecular Formula
C₅H₃BrN₂O₃
Molecular Weight
218.99 g/mol
Purity
≥ 98% (HPLC/GC)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Polyfunctionalized Nitropyridines
Appearance
Yellow to Brown Crystalline Powder or Solid
Melting Point
~150-155°C (estimated, decomposition)
Boiling Point
~341.8°C at 760 mmHg (estimated)
Density
~2.0 g/cm³ (estimated)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen or argon). Protect from strong oxidizing agents and reducing agents. Store at room temperature or 2-8°C for extended stability.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, organic synthesis, API manufacturing, kinase inhibitor synthesis, heterocyclic chemistry, nitro reduction to amino, cross-coupling reactions, selective bromine displacement, hydroxyl group derivatization, agrochemical intermediates, fine chemical production
Reactivity
Suitable for Suzuki coupling, Buchwald-Hartwig amination, Sonogashira coupling, nucleophilic aromatic substitution (preferential Br displacement), catalytic hydrogenation (nitro to amino), hydroxyl group etherification/esterification, and halogen-directed ortho-functionalization

The post 3-Bromo-4-hydroxy-5-nitropyridine appeared first on wealsunbio.

]]> https://wealsunbio.com/product/3-bromo-4-hydroxy-5-nitropyridine/feed/ 0 3-BROMO-4-CHLORO-5-NITROPYRIDINE https://wealsunbio.com/product/3-bromo-4-chloro-5-nitropyridine/ https://wealsunbio.com/product/3-bromo-4-chloro-5-nitropyridine/#respond Sat, 24 Jan 2026 12:42:43 +0000 https://wealsunbio.com/?post_type=product&p=22305 3-Bromo-4-chloro-5-nitropyridine (CAS 31872-63-6), also known as Pyridine, 3-bromo-4-chloro-5-nitro- or 3-Bromo-4-chloro-5-nitro-1-azabenzene, is a high-purity polyhalogenated nitropyridine intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features a bromine substituent at the 3-position, a chlorine atom at the 4-position, and a nitro group at the 5-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in cross-coupling reactions, nucleophilic aromatic substitution, and nitro group reduction, it exhibits excellent reactivity in Suzuki coupling, Buchwald-Hartwig amination, Sonogashira coupling, and selective halogen displacement pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, kinase inhibitor synthesis, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing polyhalogenated nitropyridine scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

The post 3-BROMO-4-CHLORO-5-NITROPYRIDINE appeared first on wealsunbio.

]]>
Product Name
3-Bromo-4-chloro-5-nitropyridine
CAS Number
31872-63-6
Chinese Name
3-溴-4-氯-5-硝基吡啶
Synonyms
Pyridine, 3-bromo-4-chloro-5-nitro-; 3-Bromo-4-chloro-5-nitro-1-azabenzene; C₅H₂BrClN₂O₂ heterocycle; MFCD07368836
Chinese Synonyms
3-溴-4-氯-5-硝基-1-氮杂苯; 溴氯硝基吡啶; 3-溴-4-氯-5-硝基吡啶
Molecular Formula
C₅H₂BrClN₂O₂
Molecular Weight
237.44 g/mol
Purity
≥ 98% (GC/HPLC)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Polyhalogenated Nitropyridines
Appearance
Yellow to Brown Crystalline Powder or Solid
Melting Point
49-50°C (literature)
Boiling Point
~285°C at 760 mmHg (estimated)
Density
~1.94 g/cm³ (estimated)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen or argon). Protect from strong oxidizing agents and reducing agents. Store at 2-8°C for extended stability.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, organic synthesis, API manufacturing, kinase inhibitor synthesis, heterocyclic chemistry, nitro reduction to amino, cross-coupling reactions, selective halogen displacement, agrochemical intermediates, fine chemical production
Reactivity
Suitable for Suzuki coupling, Buchwald-Hartwig amination, Sonogashira coupling, nucleophilic aromatic substitution (preferential Br/Cl displacement), catalytic hydrogenation (nitro to amino), and halogen-directed ortho-functionalization

The post 3-BROMO-4-CHLORO-5-NITROPYRIDINE appeared first on wealsunbio.

]]> https://wealsunbio.com/product/3-bromo-4-chloro-5-nitropyridine/feed/ 0 2-Methxy-3-nitropyridine https://wealsunbio.com/product/2-methxy-3-nitropyridine/ https://wealsunbio.com/product/2-methxy-3-nitropyridine/#respond Sat, 24 Jan 2026 12:42:21 +0000 https://wealsunbio.com/?post_type=product&p=22304 2-Methyl-3-nitropyridine (CAS 18699-87-1), also known as 3-Nitropicoline or 3-Nitro-2-picoline, is a high-purity nitro-methyl substituted pyridine intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features a methyl substituent at the 2-position and a nitro group at the 3-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in reduction reactions, nucleophilic aromatic substitution, and heterocyclic functionalization, it exhibits excellent reactivity in catalytic hydrogenation (nitro to amino), cross-coupling reactions, and electrophilic aromatic substitution pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, kinase inhibitor synthesis, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing nitromethylpyridine scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

The post 2-Methxy-3-nitropyridine appeared first on wealsunbio.

]]>
Product Name
2-Methyl-3-nitropyridine
CAS Number
18699-87-1
Chinese Name
2-甲基-3-硝基吡啶
Synonyms
3-Nitropicoline; 3-Nitro-2-picoline; Pyridine, 2-methyl-3-nitro-; 2-Methyl-3-nitro-1-azabenzene; C₆H₆N₂O₂ heterocycle; MFCD04114137
Chinese Synonyms
3-硝基-2-甲基吡啶; 2-甲基-3-硝基-1-氮杂苯; 硝基甲基吡啶; 3-硝基邻甲基吡啶; 硝基皮考啉
Molecular Formula
C₆H₆N₂O₂
Molecular Weight
138.12 g/mol
Purity
≥ 98% (GC/HPLC)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Nitromethylpyridines
Appearance
Yellow to Brown Crystalline Powder or Solid
Melting Point
24-28°C (literature)
Boiling Point
238°C (literature)
Density
1.228 g/mL at 25°C
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and reducing agents. Store sealed at 2-8°C for extended stability.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, organic synthesis, API manufacturing, kinase inhibitor synthesis, heterocyclic chemistry, nitro reduction to amino, cross-coupling reactions, agrochemical intermediates, fine chemical production
Reactivity
Suitable for catalytic hydrogenation (nitro to amino), nucleophilic aromatic substitution, electrophilic aromatic substitution, cross-coupling reactions, and methyl/nitro group derivatization

The post 2-Methxy-3-nitropyridine appeared first on wealsunbio.

]]> https://wealsunbio.com/product/2-methxy-3-nitropyridine/feed/ 0 4-Methyl-3-nitropyridine https://wealsunbio.com/product/4-methyl-3-nitropyridine/ https://wealsunbio.com/product/4-methyl-3-nitropyridine/#respond Sat, 24 Jan 2026 12:41:58 +0000 https://wealsunbio.com/?post_type=product&p=22303 4-Methyl-3-nitropyridine (CAS 5832-44-0), also known as 3-Nitro-4-methylpyridine or Pyridine, 4-methyl-3-nitro-, is a high-purity nitro-methyl substituted pyridine intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features a methyl substituent at the 4-position and a nitro group at the 3-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in reduction reactions, nucleophilic aromatic substitution, and heterocyclic functionalization, it exhibits excellent reactivity in catalytic hydrogenation (nitro to amino), cross-coupling reactions, and electrophilic aromatic substitution pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, kinase inhibitor synthesis, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing nitromethylpyridine scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

The post 4-Methyl-3-nitropyridine appeared first on wealsunbio.

]]>
Product Name
4-Methyl-3-nitropyridine
CAS Number
5832-44-0
Chinese Name
4-甲基-3-硝基吡啶
Synonyms
3-Nitro-4-methylpyridine; Pyridine, 4-methyl-3-nitro-; 4-Methyl-3-nitro-1-azabenzene; C₆H₆N₂O₂ heterocycle; MFCD00051829
Chinese Synonyms
3-硝基-4-甲基吡啶; 4-甲基-3-硝基-1-氮杂苯; 硝基甲基吡啶; 甲基硝基吡啶
Molecular Formula
C₆H₆N₂O₂
Molecular Weight
138.12 g/mol
Purity
≥ 98% (GC/HPLC)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Nitromethylpyridines
Appearance
Brown Powder or Deliquescent Crystalline Solid
Melting Point
24-28°C (literature)
Boiling Point
238°C (literature)
Density
1.228 g/mL at 25°C
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and reducing agents. Store sealed at 2-8°C for extended stability.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, organic synthesis, API manufacturing, kinase inhibitor synthesis, heterocyclic chemistry, nitro reduction to amino, cross-coupling reactions, agrochemical intermediates, fine chemical production
Reactivity
Suitable for catalytic hydrogenation (nitro to amino), nucleophilic aromatic substitution, electrophilic aromatic substitution, cross-coupling reactions, and methyl/nitro group derivatization

The post 4-Methyl-3-nitropyridine appeared first on wealsunbio.

]]> https://wealsunbio.com/product/4-methyl-3-nitropyridine/feed/ 0 N-Methyl-4-pyridinamine https://wealsunbio.com/product/n-methyl-4-pyridinamine/ https://wealsunbio.com/product/n-methyl-4-pyridinamine/#respond Sat, 24 Jan 2026 12:41:36 +0000 https://wealsunbio.com/?post_type=product&p=22302 4-(Methylamino)pyridine (CAS 1121-58-0), also known as N-Methyl-4-pyridinamine or 4-Methylaminopyridine, is a high-purity methylamino-substituted pyridine intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features a methylamino group (-NHCH₃) at the 4-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in nucleophilic substitution, reductive amination, amide coupling, and heterocyclic functionalization, it exhibits excellent reactivity in electrophilic aromatic substitution, cross-coupling reactions, and nitrogen-directed derivatization pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, kinase inhibitor synthesis, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing 4-aminopyridine scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

The post N-Methyl-4-pyridinamine appeared first on wealsunbio.

]]>
Product Name
4-(Methylamino)pyridine
CAS Number
1121-58-0
Chinese Name
4-甲氨基吡啶
Synonyms
N-Methyl-4-pyridinamine; 4-Methylaminopyridine; Pyridin-4-amine, N-methyl-; N-Methylpyridin-4-amine; C₆H₈N₂ heterocycle;
Chinese Synonyms
N-甲基-4-吡啶胺; 4-甲基氨基吡啶; 吡啶-4-胺,N-甲基-; N-甲基吡啶-4-胺; 甲氨基吡啶
Molecular Formula
C₆H₈N₂
Molecular Weight
108.14 g/mol
Purity
≥ 98% (GC/HPLC)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Methylaminopyridines
Appearance
White to Off-white Crystalline Powder or Solid
Melting Point
55-60°C (estimated)
Boiling Point
~200-205°C at 760 mmHg (estimated)
Density
~1.08 g/cm³ (estimated)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen or argon). Protect from strong oxidizing agents and acids. Store at 2-8°C for extended stability.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, organic synthesis, API manufacturing, kinase inhibitor synthesis, heterocyclic chemistry, nucleophilic substitution, reductive amination, amide coupling, agrochemical intermediates, fine chemical production
Reactivity
Suitable for electrophilic aromatic substitution, nucleophilic substitution, reductive amination, amide bond formation, cross-coupling reactions, and methylamino group derivatization

The post N-Methyl-4-pyridinamine appeared first on wealsunbio.

]]> https://wealsunbio.com/product/n-methyl-4-pyridinamine/feed/ 0 3-picolylamine https://wealsunbio.com/product/3-picolylamine/ https://wealsunbio.com/product/3-picolylamine/#respond Sat, 24 Jan 2026 12:41:15 +0000 https://wealsunbio.com/?post_type=product&p=22301 3-(Aminomethyl)pyridine (CAS 3731-52-0), also known as 3-Picolylamine or Pyridin-3-ylmethanamine, is a high-purity aminomethyl-substituted pyridine intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features an aminomethyl group at the 3-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in reductive amination, amide coupling, and heterocyclic functionalization, it exhibits excellent reactivity in nucleophilic substitution, condensation reactions, and pyridine ring derivatization pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, rodenticide intermediate synthesis (such as vacor precursors), and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing pyridylmethylamine scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

The post 3-picolylamine appeared first on wealsunbio.

]]>
Product Name
3-(Aminomethyl)pyridine
CAS Number
3731-52-0
Chinese Name
3-氨甲基吡啶
Synonyms
3-Picolylamine; Pyridin-3-ylmethanamine; 3-Pyridinemethanamine; Picolamine; 3-AMPY; C₆H₈N₂ heterocycle; MFCD00006412
Chinese Synonyms
3-吡啶甲基胺; 3-氨甲基吡啶; 吡啶-3-基甲胺; 氨甲基吡啶; 3-皮考基胺
Molecular Formula
C₆H₈N₂
Molecular Weight
108.14 g/mol
Purity
≥ 98% (GC/HPLC)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Aminomethylpyridines
Appearance
Colorless to Light Yellow Liquid
Melting Point
-21°C (literature)
Boiling Point
73-74°C at 133.3 Pa (literature)
Density
1.062 g/cm³ at 20°C
Refractive Index
n₂₀/D ~1.551
Flash Point
100°C
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen or argon). Protect from air oxidation. Store at 2-8°C for extended stability.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, organic synthesis, API manufacturing, rodenticide synthesis (vacor precursors), heterocyclic chemistry, reductive amination, amide coupling, agrochemical intermediates, fine chemical production
Reactivity
Suitable for reductive amination, amide bond formation, nucleophilic substitution, condensation with carbonyl compounds, and aminomethyl group derivatization

The post 3-picolylamine appeared first on wealsunbio.

]]> https://wealsunbio.com/product/3-picolylamine/feed/ 0 tert-Butyl 3-bromopicolinate https://wealsunbio.com/product/tert-butyl-3-bromopicolinate/ https://wealsunbio.com/product/tert-butyl-3-bromopicolinate/#respond Sat, 24 Jan 2026 12:40:52 +0000 https://wealsunbio.com/?post_type=product&p=22300 tert-Butyl 3-bromopicolinate (CAS 1260807-49-5), also known as tert-Butyl 3-bromopyridine-2-carboxylate or 2-Pyridinecarboxylic acid, 3-bromo-, 1,1-dimethylethyl ester, is a high-purity brominated pyridine ester intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features a bromine substituent at the 3-position and a tert-butyl ester group at the 2-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in cross-coupling reactions, nucleophilic aromatic substitution, and ester deprotection, it exhibits excellent reactivity in Suzuki coupling, Buchwald-Hartwig amination, Sonogashira coupling, and selective bromine displacement pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, kinase inhibitor synthesis, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing bromopyridine scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

The post tert-Butyl 3-bromopicolinate appeared first on wealsunbio.

]]>
Product Name
tert-Butyl 3-bromopicolinate
CAS Number
1260807-49-5
Chinese Name
3-溴吡啶-2-羧酸叔丁酯
Synonyms
tert-Butyl 3-bromopyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 3-bromo-, 1,1-dimethylethyl ester; 3-Bromo-2-picolinic acid tert-butyl ester; C₁₀H₁₂BrNO₂ heterocycle; MFCD09264589
Chinese Synonyms
3-溴-2-吡啶甲酸叔丁酯; 叔丁基3-溴吡啶-2-羧酸酯; 3-溴吡啶甲酸叔丁酯; 溴代吡啶甲酸叔丁酯
Molecular Formula
C₁₀H₁₂BrNO₂
Molecular Weight
258.11 g/mol
Purity
≥ 98% (GC/HPLC)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Bromopicolinates
Appearance
White to Off-white Crystalline Powder or Low-Melting Solid
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen or argon). Protect from strong oxidizing agents and bases. Store at 2-8°C for extended stability.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, organic synthesis, API manufacturing, kinase inhibitor synthesis, heterocyclic chemistry, Suzuki coupling, Buchwald-Hartwig amination, ester deprotection to acid, agrochemical intermediates, fine chemical production
Reactivity
Suitable for Suzuki coupling, Buchwald-Hartwig amination, Sonogashira coupling, nucleophilic aromatic substitution, ester hydrolysis/deprotection, and bromine-directed ortho-functionalization

The post tert-Butyl 3-bromopicolinate appeared first on wealsunbio.

]]> https://wealsunbio.com/product/tert-butyl-3-bromopicolinate/feed/ 0 Methyl 6-methoxypicolinate https://wealsunbio.com/product/methyl-6-methoxypicolinate/ https://wealsunbio.com/product/methyl-6-methoxypicolinate/#respond Sat, 24 Jan 2026 12:40:29 +0000 https://wealsunbio.com/?post_type=product&p=22299 Methyl 6-methoxypicolinate (CAS 26256-72-4), also known as Methyl 6-methoxypyridine-2-carboxylate or 6-Methoxy-2-pyridinecarboxylic acid methyl ester, is a high-purity methoxypyridine ester intermediate widely used in pharmaceutical synthesis, organic chemistry research, agrochemical development, and fine chemical manufacturing. This compound features a methoxy substituent at the 6-position and a methyl ester group at the 2-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in ester hydrolysis, nucleophilic aromatic substitution, and cross-coupling reactions, it exhibits excellent reactivity in Suzuki coupling, Buchwald-Hartwig amination, amide formation, and selective methoxy displacement pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, kinase inhibitor synthesis, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing methoxypyridine scaffolds, heterocyclic kinase inhibitor intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

The post Methyl 6-methoxypicolinate appeared first on wealsunbio.

]]>
Product Name
Methyl 6-methoxypicolinate
CAS Number
26256-72-4
Chinese Name
6-甲氧基吡啶-2-羧酸甲酯
Synonyms
Methyl 6-methoxypyridine-2-carboxylate; 6-Methoxy-2-pyridinecarboxylic acid methyl ester; Pyridine-2-carboxylic acid, 6-methoxy-, methyl ester; Methyl 6-methoxy-2-picolinate; C₈H₉NO₃ heterocycle; MFCD07779517
Chinese Synonyms
6-甲氧基-2-吡啶甲酸甲酯; 甲基6-甲氧基吡啶-2-羧酸酯; 6-甲氧基吡啶甲酸甲酯; 甲氧基吡啶甲酸甲酯
Molecular Formula
C₈H₉NO₃
Molecular Weight
167.16 g/mol
Purity
≥ 98% (GC/HPLC)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Methoxypicolinates
Appearance
White to Off-white Crystalline Powder or Low-Melting Solid
Melting Point
33-39°C (literature)
Boiling Point
~260-265°C at 760 mmHg (estimated)
Density
~1.16 g/cm³ (estimated)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and bases. Store sealed at 2-8°C for extended stability.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, organic synthesis, API manufacturing, kinase inhibitor synthesis, heterocyclic chemistry, ester hydrolysis to acid, nucleophilic aromatic substitution, agrochemical intermediates, fine chemical production
Reactivity
Suitable for ester hydrolysis to acid, amide formation, Suzuki coupling, Buchwald-Hartwig amination, nucleophilic aromatic substitution, and methoxy-directed ortho-functionalization

The post Methyl 6-methoxypicolinate appeared first on wealsunbio.

]]> https://wealsunbio.com/product/methyl-6-methoxypicolinate/feed/ 0