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2-(3-Chlorophenoxy)-propionic acid

2-(3-Chlorophenoxy)propionic acid (CAS 101-10-0), commonly known as Cloprop, is a high-purity chlorophenoxy carboxylic acid intermediate widely used in pharmaceutical synthesis, agrochemical development, plant growth regulator manufacturing, and fine chemical production. This compound features a chlorine substituent at the meta-position of the phenoxy group and a propionic acid side chain, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in esterification, amide coupling, and functional group transformations, it exhibits excellent reactivity in nucleophilic substitution, cross-coupling reactions, and derivatization pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, agrochemical formulation, medicinal chemistry research, and scale-up production. This compound is particularly valuable in the synthesis of plant growth regulators, herbicide intermediates, pharmaceuticals containing chlorophenoxy scaffolds, and specialty chemical precursors.

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Product Name
2-(3-Chlorophenoxy)propionic acid
CAS Number
101-10-0
Chinese Name
调果酸
Synonyms
Cloprop; 2-(3-Chlorophenoxy)propanoic acid; 3-Chlorophenoxypropionic acid; m-Chlorophenoxypropionic acid; α-(3-Chlorophenoxy)propionic acid; 2-(m-Chlorophenoxy)propionic acid; DL-2-(3-Chlorophenoxy)propionic acid; 3-CPA; α-(m-Chlorophenoxy)propionic acid
Chinese Synonyms
2-(3-氯苯氧基)丙酸; 间氯苯氧基丙酸; α-(3-氯苯氧基)丙酸; 调果酸; 3-氯苯氧基丙酸; 间氯苯氧基丙酸
Molecular Formula
C₉H₉ClO₃
Molecular Weight
200.62 g/mol
Purity
≥ 98% (HPLC/GC)
Product Category
Pharmaceutical Intermediates / Benzene Derivatives / Chlorophenoxy Acids
Appearance
White to Off-white Crystalline Powder
Melting Point
105-108°C (literature)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and bases.
Shelf Life
24 months under recommended storage conditions
Packaging
1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, agrochemical intermediates, plant growth regulator synthesis, herbicide development, esterification reactions, amide coupling, fine chemical production, organic synthesis
Reactivity
Suitable for esterification, amide bond formation, nucleophilic substitution, cross-coupling reactions, and chlorophenoxy-directed functionalization