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4-Bromo-2-nitrobenzylalcohol
4-Bromo-2-nitrobenzyl alcohol (CAS 22996-19-6), also known as (4-Bromo-2-nitrophenyl)methanol or 2-Nitro-4-bromobenzyl alcohol, is a high-purity bromo-nitro substituted benzyl alcohol intermediate widely used in pharmaceutical synthesis, organic chemistry research, and fine chemical manufacturing. This compound features a bromine substituent at the para-position and a nitro group at the ortho-position of the benzyl alcohol structure, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in reduction reactions, nucleophilic substitution, and functional group transformations, it exhibits excellent reactivity in catalytic hydrogenation (nitro to amino), esterification, etherification, and cross-coupling pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing bromo-nitro aromatic scaffolds, heterocyclic intermediates, agrochemical precursors, and specialty chemical precursors. As a reliable benzene derivative intermediate from our product line, it serves as an important precursor for constructing functionalized aromatic systems in drug discovery and fine chemical development programs.
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Product Name
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4-Bromo-2-nitrobenzyl alcohol
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CAS Number
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22996-19-6
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Chinese Name
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4-溴-2-硝基苄醇
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Synonyms
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(4-Bromo-2-nitrophenyl)methanol; 2-Nitro-4-bromobenzyl alcohol; Benzyl alcohol, 4-bromo-2-nitro-; 4-Bromo-2-nitrophenylmethanol; 2-Nitro-4-bromo-α-hydroxytoluene; 1-(Hydroxymethyl)-4-bromo-2-nitrobenzene; p-Bromo-o-nitrobenzyl alcohol; 4-Br-2-NO₂-benzyl alcohol
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Chinese Synonyms
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2-硝基-4-溴苄醇; 4-溴-2-硝基苯甲醇; 1-(羟甲基)-4-溴-2-硝基苯; 对溴邻硝基苯甲醇; 4-溴-2-硝基-α-羟基甲苯
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Molecular Formula
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C₇H₆BrNO₃
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Molecular Weight
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204.03 g/mol
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Purity
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≥ 98% (HPLC)
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Product Category
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Pharmaceutical Intermediates / Benzene Derivatives / Nitrobenzyl Alcohols
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Appearance
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Light Yellow to Yellow Crystalline Powder or Solid
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Melting Point
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80-85°C (estimated)
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Storage Conditions
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Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and reducing agents.
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Shelf Life
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24 months under recommended storage conditions
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Packaging
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1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
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Applications
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Pharmaceutical intermediates, organic synthesis, API manufacturing, nitro reduction reactions, nucleophilic substitution, esterification, etherification, heterocyclic synthesis, agrochemical intermediates, fine chemical production
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Reactivity
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Suitable for catalytic hydrogenation (nitro to amino), esterification, etherification, nucleophilic substitution, oxidation to aldehyde/acid, and bromo/nitro-directed ortho-functionalization
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