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4-CHLORO-3-NITROBENZYL ALCOHOL
4-Chloro-3-nitrobenzyl alcohol (CAS 55912-20-4) is a high-purity chloro-nitro substituted benzyl alcohol intermediate widely used in pharmaceutical synthesis, organic chemistry research, and fine chemical manufacturing. This compound features a chlorine substituent at the para-position and a nitro group at the meta-position of the benzyl alcohol structure, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in reduction reactions, nucleophilic substitution, and functional group transformations, it exhibits excellent reactivity in catalytic hydrogenation (nitro to amino), esterification, etherification, and cross-coupling pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing chloro-nitro aromatic scaffolds, agrochemical intermediates, and specialty chemical precursors. As a reliable benzene derivative intermediate, it serves as an important precursor for constructing functionalized aromatic systems in drug discovery and fine chemical development programs.
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Product Name
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4-Chloro-3-nitrobenzyl alcohol
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CAS Number
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55912-20-4
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Chinese Name
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4-氯-3-硝基苯甲醇
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Synonyms
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(4-Chloro-3-nitrophenyl)methanol; Benzyl alcohol, 4-chloro-3-nitro-; 4-Chloro-3-nitrobenzenemethanol; 3-Nitro-4-chlorobenzyl alcohol; 4-Chloro-m-nitrobenzyl alcohol; 1-(Hydroxymethyl)-4-chloro-3-nitrobenzene; 4-Cl-3-NO₂-benzyl alcohol
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Chinese Synonyms
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3-硝基-4-氯苯甲醇; 4-氯-3-硝基苄醇; 1-(羟甲基)-4-氯-3-硝基苯; 对氯间硝基苯甲醇
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Molecular Formula
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C₇H₆ClNO₃
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Molecular Weight
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187.58 g/mol
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Purity
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≥ 98% (HPLC)
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Product Category
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Pharmaceutical Intermediates / Benzene Derivatives / Nitrobenzyl Alcohols
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Appearance
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Light Yellow to Yellow Crystalline Powder or Solid
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Melting Point
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95-99°C (estimated)
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Storage Conditions
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Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and reducing agents.
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Shelf Life
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24 months under recommended storage conditions
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Packaging
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1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
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Applications
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Pharmaceutical intermediates, organic synthesis, API manufacturing, nitro reduction reactions, nucleophilic substitution, esterification, etherification, agrochemical intermediates, fine chemical production
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Reactivity
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Suitable for catalytic hydrogenation (nitro to amino), esterification, etherification, nucleophilic substitution, oxidation to aldehyde/acid, and chloro-directed ortho-functionalization
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