Benzyl 2-bromoethylcarbamate

Benzyl 2-bromoethylcarbamate (CAS 53844-02-3), also known as Benzyl N-(2-bromoethyl)carbamate or 2-Bromoethyl carbamic acid benzyl ester, is a high-purity bromoalkyl carbamate intermediate widely used in pharmaceutical synthesis, organic chemistry research, and fine chemical manufacturing. This compound features a benzyloxycarbonyl (Cbz) protected amine functionality linked to a reactive bromoethyl side chain, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in nucleophilic substitution reactions, amine protection/deprotection chemistry, and functional group transformations, it exhibits excellent reactivity in alkylation reactions, amide coupling, and Cbz deprotection pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing protected aminoethyl scaffolds, heterocyclic intermediates, peptide mimetics, and specialty chemical precursors. As a reliable benzene derivative intermediate from our product line, it serves as an important precursor for constructing Cbz-protected amino-functionalized systems in drug discovery and fine chemical development programs.

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Product Name	Benzyl 2-bromoethylcarbamate
CAS Number	53844-02-3
Chinese Name	2-溴乙基氨基甲酸苄酯
Synonyms	Benzyl N-(2-bromoethyl)carbamate; Carbamic acid, N-(2-bromoethyl)-, phenylmethyl ester; 2-Bromoethyl carbamic acid benzyl ester; Benzyl (2-bromoethyl)carbamate; N-(2-Bromoethyl)-O-benzyl carbamate; Cbz-NH-CH₂CH₂Br; Benzyl 2-bromoethylurethane
Chinese Synonyms	N-(2-溴乙基)氨基甲酸苄酯; 苄基(2-溴乙基)氨基甲酸酯; 溴乙基苄基氨基甲酸酯; 2-溴乙基苄氧羰基胺; Cbz-2-溴乙胺
Molecular Formula	C₁₀H₁₂BrNO₂
Molecular Weight	258.11 g/mol
Purity	≥ 98% (HPLC/GC)
Product Category	Pharmaceutical Intermediates / Benzene Derivatives / Carbamate Esters
Appearance	White to Off-white Crystalline Powder or Solid
Melting Point	45-50°C (estimated)
Storage Conditions	Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong bases and nucleophiles.
Shelf Life	24 months under recommended storage conditions
Packaging	1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
Applications	Pharmaceutical intermediates, organic synthesis, API manufacturing, amine protection chemistry, nucleophilic substitution, heterocyclic synthesis, peptide mimetics, fine chemical production
Reactivity	Suitable for nucleophilic substitution (bromo group), Cbz deprotection (hydrogenolysis), amide coupling, alkylation reactions, and carbamate-directed functionalization