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Benzyl carbamate

Benzyl carbamate (CAS 621-84-1) is a high-purity carbamate ester intermediate widely used in pharmaceutical synthesis and organic chemistry research. This compound serves as a versatile protecting group reagent and building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). Featuring a benzyloxycarbonyl (Cbz/Z) functional group, it exhibits excellent stability and reactivity in peptide synthesis, amine protection/deprotection chemistry, and various nucleophilic substitution reactions. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, and scale-up production. This compound is particularly valuable in the synthesis of peptide-based pharmaceuticals, amino acid derivatives, and fine chemicals requiring carbamate functionality.

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Product Name
Benzyl carbamate
CAS Number
621-84-1
Chinese Name
氨基甲酸苄酯
Synonyms
Cbz-NH₂; Z-NH₂; Carbamic acid, phenylmethyl ester; Phenylmethyl carbamate; Benzyl urethane; N-Cbz-ammonia; Benzyloxycarbonyl amine; Cbz-amine; Z-amine
Chinese Synonyms
苄氧羰基胺; Cbz-胺; Z-胺; 氨基甲酸苯甲酯; 苄基氨基甲酸酯
Molecular Formula
C₈H₉NO₂
Molecular Weight
151.16 g/mol
Purity
≥ 98%
Product Category
Pharmaceutical Intermediates / Carbamates / Protecting Group Reagents
Appearance
White to Off-white Crystalline Powder
Melting Point
88-90°C
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed.
Shelf Life
24 months under recommended storage conditions
Packaging
1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
Applications
Pharmaceutical intermediates, peptide synthesis, amine protection chemistry, organic synthesis, API manufacturing, fine chemical production
Reactivity
Suitable for Cbz protection of amines, peptide coupling reactions, nucleophilic substitution, and deprotection under hydrogenolysis conditions
Special Note
Widely used protecting group reagent in peptide and protein chemistry