BENZYL N-(2-HYDROXYETHYL)CARBAMATE

Benzyl N-(2-hydroxyethyl)carbamate (CAS 77987-49-6), also known as N-Cbz-ethanolamine or 2-Hydroxyethyl carbamic acid benzyl ester, is a high-purity Cbz-protected amino alcohol intermediate widely used in pharmaceutical synthesis, peptide chemistry, organic chemistry research, and fine chemical manufacturing. This compound features a benzyloxycarbonyl (Cbz/Z) protected amine functionality linked to a hydroxyethyl side chain, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in amine protection/deprotection chemistry, esterification, and functional group transformations, it exhibits excellent reactivity in amide coupling, etherification, Cbz deprotection, and nucleophilic substitution pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, peptide synthesis, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing protected aminoethanol scaffolds, heterocyclic intermediates, polymer modifiers, and specialty chemical precursors.

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Product Name	Benzyl N-(2-hydroxyethyl)carbamate
CAS Number	77987-49-6
Chinese Name	N-(苄氧羰基氨基)-1-乙醇
Synonyms	N-Cbz-ethanolamine; Cbz-ethanolamine; 2-Hydroxyethyl carbamic acid benzyl ester; Carbamic acid, N-(2-hydroxyethyl)-, phenylmethyl ester; Benzyl (2-hydroxyethyl)carbamate; N-(2-Hydroxyethyl)-O-benzyl carbamate; Cbz-NH-CH₂CH₂OH; Benzyl 2-hydroxyethylurethane; Z-ethanolamine
Chinese Synonyms	N-苄氧羰基乙醇胺; Cbz-乙醇胺; 2-羟乙基氨基甲酸苄酯; 苄基(2-羟乙基)氨基甲酸酯; N-(2-羟乙基)氨基甲酸苄酯; Z-乙醇胺; 苄氧羰基氨基乙醇
Molecular Formula	C₁₀H₁₃NO₃
Molecular Weight	195.21 g/mol
Purity	≥ 98% (HPLC)
Product Category	Pharmaceutical Intermediates / Benzene Derivatives / Carbamate Esters
Appearance	White to Off-white Crystalline Powder or Solid
Melting Point	55-60°C (estimated)
Storage Conditions	Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong acids and bases.
Shelf Life	24 months under recommended storage conditions
Packaging	1kg/foil bag, 5kg/drum, 25kg/drum, or customized according to customer requirements
Applications	Pharmaceutical intermediates, peptide synthesis, organic synthesis, API manufacturing, amine protection chemistry, esterification, etherification, heterocyclic synthesis, polymer modifiers, fine chemical production
Reactivity	Suitable for Cbz deprotection (hydrogenolysis), esterification, etherification, amide coupling, nucleophilic substitution, and carbamate-directed functionalization