Biomedical and Chemical Materials|Wealsun Biotech https://wealsunbio.com/product/ Sun, 01 Mar 2026 10:49:34 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://wealsunbio.com/wp-content/uploads/2025/06/20260211161228_5028_5-e1770797653670.png Biomedical and Chemical Materials|Wealsun Biotech https://wealsunbio.com/product/ 32 32 BENZYL ETHYL ETHER https://wealsunbio.com/product/benzyl-ethyl-ether/ https://wealsunbio.com/product/benzyl-ethyl-ether/#respond Sun, 22 Feb 2026 14:13:53 +0000 https://wealsunbio.com/?post_type=product&p=23098 Benzyl ethyl ether (CAS 539-30-0) is a versatile aromatic ether engineered for organic synthesis, protecting group chemistry, and specialty solvent applications. This molecule integrates a benzyl moiety—a benzylic carbon with enhanced reactivity toward radical or electrophilic processes—with an ethyl ether linkage, creating a stable yet functionally tunable architecture. The benzylic C–H bonds are susceptible to selective oxidation or halogenation, enabling downstream diversification to compounds such as benzaldehyde and benzyl alcohol. As a protecting group precursor, benzyl ethyl ether can be cleaved under hydrogenolytic or Lewis acidic conditions to release benzyl-protected alcohols, making it valuable for orthogonal deprotection strategies in complex molecule synthesis. It is also recognized as a food-grade flavoring agent (FEMA 2144) with a powerful, fruity aroma, found naturally in cocoa and used in fragrance applications. This intermediate is particularly valuable for constructing pharmaceutical intermediates, fragrance compounds, and polymer additives where the benzyl-ether motif balances stability with controlled reactivity. Manufactured under controlled conditions, it supports synthetic programs requiring reliable ether solvents or benzylating reagents with well-defined physicochemical properties.

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Product Name
Benzyl ethyl ether
CAS Number
539-30-0
Chinese Name
苄基乙基醚
Synonyms
Ethoxy(methyl)benzene; (Ethoxymethyl)benzene; Benzyl ethyl ether; Ethoxymethylbenzene
Chinese Synonyms
乙氧基甲基苯; 苄基乙基醚; 乙基苄基醚; 苯甲氧基乙烷
Molecular Formula
C₉H₁₂O
Molecular Weight
136.19 g/mol 
Purity
≥ 98% (GC area normalization)
Product Category
Fine Chemicals / Organic Solvents / Benzyl Ether Derivatives
Appearance
Colorless to Pale Yellow Liquid
Boiling Point
~185-190°C at 760 mmHg (literature)
Density
~0.96 g/cm³ at 20°C (estimated)
Refractive Index
n₂₀/D ~1.49 (estimated)
Flash Point
~65-70°C (closed cup, estimated)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen). Protect from strong oxidizing agents and acids to avoid ether cleavage or benzylic oxidation.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements (amber glass recommended for light-sensitive batches)
Applications
Organic synthesis solvent, benzyl protecting group reagent, fragrance/intermediate synthesis, polymer additive precursor, phase-transfer catalysis medium, benzylic functionalization studies
Reactivity
Suitable for benzylic bromination/oxidation, ether cleavage (HI, BBr₃), hydrogenolysis (Pd/C, H₂), electrophilic aromatic substitution on phenyl ring, and use as inert solvent for organometallic reactions
Special Note
✅ Benzylic Ether Scaffold—benzylic C–H enables selective functionalization; ether linkage provides stability. Flammable liquid—handle away from ignition sources. Part of our benzyl ether building block series.

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]]> https://wealsunbio.com/product/benzyl-ethyl-ether/feed/ 0 3-(4-Chlorobenzoyl)propionic acid https://wealsunbio.com/product/3-4-chlorobenzoylpropionic-acid/ https://wealsunbio.com/product/3-4-chlorobenzoylpropionic-acid/#respond Sun, 22 Feb 2026 14:07:48 +0000 https://wealsunbio.com/?post_type=product&p=23097 3-(4-Chlorobenzoyl)propionic acid (CAS 3984-34-7) is a strategically functionalized γ-keto acid engineered for heterocyclic construction, pharmaceutical intermediate synthesis, and agrochemical development. This molecule integrates a 4-chlorophenyl core—a halogenated aromatic system with enhanced metabolic stability—with a benzoyl ketone linker and a terminal propionic acid moiety. The γ-keto acid architecture (Ar-CO-CH₂-CH₂-COOH) serves as a privileged scaffold for Paal-Knorr pyrrole synthesis, Friedländer quinoline construction, and Knoevenagel condensation reactions. The 4-chloro substituent provides an additional handle for late-stage functionalization via cross-coupling or nucleophilic aromatic substitution, while the carboxylic acid terminus enables salt formation, amide coupling, or esterification for formulation optimization. This intermediate is particularly valuable for constructing NSAID analogs, PPAR modulators, antifungal agents, and herbicide scaffolds where the chlorobenzoyl-propionic acid motif balances lipophilicity with versatile synthetic reactivity. Manufactured with purity ≥98% under controlled conditions, it supports drug discovery programs requiring modular access to halogenated keto-acid architectures with defined substitution patterns.

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Product Name
3-(4-Chlorobenzoyl)propionic acid
CAS Number
3984-34-7
Chinese Name
3-(4-氯苯甲酰基) 丙酸
Synonyms
4-Chlorobenzoylpropionic acid; 4-(4-Chlorophenyl)-4-oxobutanoic acid; γ-(4-Chlorobenzoyl)butyric acid; C₁₀H₉ClO₃ keto-acid
Chinese Synonyms
4-氯苯甲酰丙酸; 4-(4-氯苯基)-4-氧代丁酸; γ-(4-氯苯甲酰) 丁酸; 氯代酮酸中间体
Molecular Formula
C₁₀H₉ClO₃
Molecular Weight
212.63 g/mol
Purity
≥ 98% (HPLC area normalization)
Product Category
Pharmaceutical Intermediates / Halogenated Aromatic Acids / Keto-Acid Derivatives
Appearance
White to orange to green crystalline powder
Melting Point
~ 142-146°C (literature reference recommended)
pKa
~4.39 ± 0.10 (carboxylic acid, estimated)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong bases to avoid decarboxylation or Claisen condensation side reactions.
Shelf Life
24 months under recommended storage conditions
Packaging
100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications
Heterocyclic synthesis (pyrroles/quinolines via Paal-Knorr/Friedländer), NSAID analog development, PPAR modulator research, agrochemical intermediate synthesis, Knoevenagel condensation precursor, amide coupling for drug conjugates
Reactivity
Suitable for Paal-Knorr pyrrole synthesis, Friedländer quinoline construction, Knoevenagel condensation, amide coupling (activation via EDC/HATU), esterification, decarboxylative coupling, and electrophilic aromatic substitution on the chlorophenyl ring

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]]> https://wealsunbio.com/product/3-4-chlorobenzoylpropionic-acid/feed/ 0 3,5-Dibromo-2-pyridylamine https://wealsunbio.com/product/35-dibromo-2-pyridylamine/ https://wealsunbio.com/product/35-dibromo-2-pyridylamine/#respond Sun, 22 Feb 2026 13:55:40 +0000 https://wealsunbio.com/?post_type=product&p=23096 3,5-Dibromo-2-pyridylamine (CAS 35486-42-1), also known as 2-Amino-3,5-dibromopyridine, is a strategically functionalized halogenated heterocyclic scaffold engineered for cross-coupling reactions, pharmaceutical intermediate development, and ligand synthesis. This molecule integrates a pyridine core—a nitrogen-containing six-membered aromatic ring—with an amino substituent at the C2 position and two bromine atoms at the C3 and C5 positions. The C2-amino group provides nucleophilic reactivity for acylation, alkylation, diazotization, or heterocyclic fusion, while the dual bromine handles enable sequential or simultaneous Pd-catalyzed cross-coupling (Suzuki, Stille, Negishi, Sonogashira) to introduce diverse aryl, alkyl, or heteroaryl groups. This tri-functional architecture offers orthogonal reactivity patterns, making it particularly valuable for constructing kinase inhibitor cores, agrochemical actives, and asymmetric ligands where differentiated synthetic strategies are required. Compared to dibromopyridines without amino groups, this compound provides additional derivatization pathways through the nucleophilic nitrogen. Manufactured with purity ≥98% under controlled conditions, it supports drug discovery and materials science programs requiring modular access to differentially functionalized pyridine architectures.

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Product Name
3,5-Dibromo-2-pyridylamine
CAS Number
35486-42-1
Chinese Name
3,5-二溴 -2-吡啶胺
Synonyms
2-Amino-3,5-dibromopyridine; Pyridin-2-amine, 3,5-dibromo-; 2-Pyridylamine, 3,5-dibromo-
Chinese Synonyms
2-氨基 -3,5-二溴吡啶; 3,5-二溴 -2-氨基吡啶; 二溴氨基吡啶; 3,5-二溴氮苯 -2-胺
Molecular Formula
C₅H₄Br₂N₂
Molecular Weight
251.91 g/mol 
Purity
≥ 98% (GC/HPLC area normalization)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Halogenated Aminopyridines
Appearance
White to Off-white to Pale Yellow Crystalline Powder
Melting Point
~155 – 157 °C (literature reference recommended)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen). Protect from strong oxidizing agents and acids to avoid amino group oxidation or diazotization.
Shelf Life
24 months under recommended storage conditions
Packaging
100mg/vial, 500mg/vial, 1g/bottle, 5g/bottle, or customized according to customer requirements
Applications
Kinase inhibitor scaffold development, agrochemical intermediate synthesis, Pd-catalyzed cross-coupling (C3/C5-Br), amino group derivatization (acylation/alkylation), heterocyclic library construction, asymmetric ligand synthesis
Reactivity
Suitable for Suzuki coupling, Stille coupling, Negishi coupling (C3/C5-Br displacement), amino group acylation/alkylation, diazotization, heterocyclic fusion, and electrophilic aromatic substitution at C4/C6
Special Note
✅ Tri-Functional Scaffold—C2-NH₂ for nucleophilic derivatization, C3/C5-Br for cross-coupling. Orthogonal Reactivity—amino and bromo groups can be independently modified. Distinct from dibromopyridines by amino functionality. Part of our halogenated aminopyridine series.

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]]> https://wealsunbio.com/product/35-dibromo-2-pyridylamine/feed/ 0 3-Bromoquinoline https://wealsunbio.com/product/3-bromoquinoline/ https://wealsunbio.com/product/3-bromoquinoline/#respond Sun, 22 Feb 2026 13:49:24 +0000 https://wealsunbio.com/?post_type=product&p=23095 3-Bromoquinoline (CAS 5332-24-1) is a strategically functionalized fused bicyclic heterocyclic scaffold engineered for cross-coupling reactions, pharmaceutical intermediate development, and materials science applications. This molecule integrates a quinoline core—a fused benzene-pyridine bicyclic system prevalent in bioactive natural products and pharmaceuticals (including antimalarial drugs like quinine and chloroquine)—with a bromine substituent at the C3 position. The C3-bromo handle serves as a privileged site for Pd-catalyzed cross-coupling (Suzuki, Stille, Negishi, Sonogashira), enabling efficient introduction of diverse aryl, alkyl, or heteroaryl groups to the quinoline scaffold. The fused bicyclic architecture provides enhanced rigidity, extended π-conjugation, and improved metabolic stability compared to monocyclic pyridine analogs, making it particularly valuable for constructing kinase inhibitor cores, antimalarial agents, antimicrobial compounds, and functional materials where the quinoline motif offers superior target binding affinity and photophysical properties. Compared to halogenated pyridines, quinoline derivatives provide expanded aromatic surface area for π-stacking interactions and distinct electronic distribution across the fused ring system. Manufactured with purity ≥98% under controlled conditions, it supports drug discovery and materials science programs requiring modular access to functionalized quinoline architectures.

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Product Name
3-Bromoquinoline
CAS Number
5332-24-1
Chinese Name
3-溴喹啉
Synonyms
Quinoline, 3-bromo-; 3-Bromoquinoline; C₉H₆BrN heterocycle; 3-Bromo-1-azanaphthalene
Chinese Synonyms
3-溴 -1-氮杂萘; 溴喹啉; 3-位溴代喹啉; 喹啉 -3-溴
Molecular Formula
C₉H₆BrN
Molecular Weight
208.05 g/mol
Purity
≥ 98% (GC/HPLC area normalization)
Product Category
Pharmaceutical Intermediates / Quinoline Derivatives / Halogenated Heterocycles
Appearance
Clear colorless to yellow liquid
Melting Point
~26-30°C (literature reference recommended)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen). Protect from strong oxidizing agents and bases to avoid oxidation or substitution.
Shelf Life
24 months under recommended storage conditions
Packaging
100mg/vial, 500mg/vial, 1g/bottle, 5g/bottle, or customized according to customer requirements
Applications
Kinase inhibitor scaffold development, antimalarial drug synthesis (chloroquine analogs), agrochemical intermediate, Pd-catalyzed cross-coupling (C3-Br), functional material precursor, heterocyclic library construction
Reactivity
Suitable for Suzuki coupling, Stille coupling, Negishi coupling, Sonogashira coupling (C3-Br displacement), electrophilic aromatic substitution at C5/C6/C7/C8, and directed lithiation
Special Note
✅ Fused Bicyclic Scaffold—extended π-system vs. monocyclic pyridines. C3-Br offers strategic functionalization site. Distinct from pyridine derivatives by benzene fusion. Part of our halogenated quinoline series.

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]]> https://wealsunbio.com/product/3-bromoquinoline/feed/ 0 2-Bromo-6-methoxypyridine https://wealsunbio.com/product/2-bromo-6-methoxypyridine/ https://wealsunbio.com/product/2-bromo-6-methoxypyridine/#respond Sun, 22 Feb 2026 13:40:12 +0000 https://wealsunbio.com/?post_type=product&p=23094 2-Bromo-6-methoxypyridine (CAS 40473-07-2) is a strategically asymmetric halogenated heterocyclic scaffold engineered for cross-coupling reactions, ligand synthesis, and pharmaceutical intermediate development. This molecule integrates a pyridine core—a nitrogen-containing six-membered aromatic ring—with a bromine substituent at the C2 position and a methoxy group at the C6 position. The C2-bromo handle is activated by the adjacent ring nitrogen, enabling efficient Pd-catalyzed cross-coupling (Suzuki, Stille, Negishi, Sonogashira) to introduce diverse aryl, alkyl, or heteroaryl groups. The C6-methoxy group serves as an electron-donating substituent that modulates the electronic properties of the pyridine ring, provides steric bulk, and can serve as a protected phenol equivalent (demethylatable to hydroxyl for further functionalization). This 2,6-disubstitution pattern offers a distinct geometry compared to symmetric dibromopyridines, making it particularly valuable for constructing asymmetric ligands, kinase inhibitor cores, and agrochemical actives where specific electronic and steric environments are required. Manufactured under controlled conditions, it supports drug discovery and materials science programs requiring modular access to differentially functionalized pyridine architectures.

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Product Name
2-Bromo-6-methoxypyridine
CAS Number
40473-07-2
Chinese Name
2-溴 -6-甲氧基吡啶
Synonyms
6-Methoxy-2-bromopyridine; Pyridine, 2-bromo-6-methoxy-; C₆H₆BrNO heterocycle; 2-Bromo-6-methoxypyridine
Chinese Synonyms
6-甲氧基 -2-溴吡啶; 溴甲氧基吡啶; 2-溴 -6-甲氧基氮苯; 不对称二取代吡啶
Molecular Formula
C₆H₆BrNO
Molecular Weight
188.02 g/mol
Purity
≥ 98% (GC/HPLC area normalization)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Halogenated Heterocycles
Appearance
Colorless to Pale Yellow Liquid or Low-Melting Solid
Boiling Point
~230-240°C at 760 mmHg (estimated)
Density
~1.55 g/cm³ (estimated)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen). Protect from strong acids (to avoid demethylation) and strong bases/nucleophiles (to avoid substitution).
Shelf Life
24 months under recommended storage conditions
Packaging
100mg/vial, 500mg/vial, 1g/bottle, 5g/bottle, or customized according to customer requirements
Applications
Kinase inhibitor scaffold development, asymmetric ligand synthesis, agrochemical intermediate, Pd-catalyzed cross-coupling (C2-Br), demethylation to hydroxyl derivative, heterocyclic library construction
Reactivity
Suitable for Suzuki coupling, Stille coupling, Negishi coupling (C2-Br displacement), O-demethylation (e.g., BBr₃), electrophilic aromatic substitution at C3/C4/C5, and directed lithiation
Special Note
✅ Asymmetric 2,6-Disubstituted Scaffold—C2-Br for coupling, C6-OMe for electronic modulation/protection. Distinct from symmetric 2,6-dibromopyridine (CAS 626-05-1) by electronic properties. Part of our halogenated pyridine series.

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]]> https://wealsunbio.com/product/2-bromo-6-methoxypyridine/feed/ 0 2-Hydroxy-5-bromopyridine https://wealsunbio.com/product/2-hydroxy-5-bromopyridine/ https://wealsunbio.com/product/2-hydroxy-5-bromopyridine/#respond Sun, 22 Feb 2026 13:35:44 +0000 https://wealsunbio.com/?post_type=product&p=23093 2-Hydroxy-5-bromopyridine (CAS 13466-38-1) is a strategically functionalized pyridine scaffold engineered for pharmaceutical intermediate synthesis, cross-coupling reactions, and heterocyclic diversification . This molecule exists in tautomeric equilibrium between the 2-hydroxypyridine and 2-pyridone forms, integrating a bromine substituent at the C5 position of the pyridine ring. The C5-bromo handle is activated for Pd-catalyzed cross-coupling (Suzuki, Buchwald-Hartwig, Sonogashira) while the 2-hydroxy/oxo group enables hydrogen-bonding interactions and serves as a handle for etherification or alkylation . The compound features an electron-rich C-5 position that enables selective copper-catalyzed C–N bond formation with amines, heterocycles, and amides under mild conditions using inexpensive 1,2-diol ligands such as ethylene glycol . This intermediate is particularly valuable for constructing pharmaceutical actives, agrochemical ingredients, and functional materials where the 2-hydroxy-5-bromo motif enables modular synthetic strategies. Manufactured under controlled conditions, it supports drug discovery and chemical development programs requiring access to functionalized pyridine architectures

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Product Name
2-Hydroxy-5-bromopyridine
CAS Number
13466-38-1
Chinese Name
2-羟基 -5-溴吡啶
Synonyms
5-Bromo-2-pyridinol; 5-Bromo-2-hydroxypyridine; 5-Bromopyridin-2-ol;
Chinese Synonyms
5-溴 -2-吡啶醇; 5-溴 -2-羟基吡啶; 溴羟基吡啶; 2-羟基 -5-溴氮苯
Molecular Formula
C₅H₄BrNO
Molecular Weight
174g/mol
Purity
≥ 98% (HPLC/GC area normalization)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Halogenated Hydroxypyridines
Appearance
White to Off-white Crystalline Powder or Solid
Melting Point
~180-185°C (literature reference recommended; may exist as pyridone tautomer)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen). Protect from strong oxidizing agents and bases to avoid oxidation or substitution.
Shelf Life
24 months under recommended storage conditions
Packaging
100mg/vial, 500mg/vial, 1g/bottle, 5g/bottle, or customized according to customer requirements
Applications
Kinase inhibitor scaffold development, agrochemical intermediate synthesis, Pd-catalyzed cross-coupling (C5-Br), triflate formation (C2-OH), heterocyclic library construction, functional material precursor
Reactivity
Suitable for Suzuki coupling, Stille coupling, Negishi coupling (C5-Br displacement), triflation (C2-OH to OTf), O-alkylation, tautomerization control, and electrophilic aromatic substitution at C3/C4/C6
Special Note
✅ Dual-Functionality Scaffold—C5-Br for coupling, C2-OH for triflation/alkylation. Tautomeric Equilibrium—exists as 2-hydroxypyridine/2-pyridone forms. Distinct from dibromopyridines by OH/Br differentiation. Part of our halogenated pyridine series.

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]]> https://wealsunbio.com/product/2-hydroxy-5-bromopyridine/feed/ 0 3,5-Dibromopyridine https://wealsunbio.com/product/35-dibromopyridine/ https://wealsunbio.com/product/35-dibromopyridine/#respond Sun, 22 Feb 2026 13:31:02 +0000 https://wealsunbio.com/?post_type=product&p=23092 3,5-Dibromopyridine (CAS 625-92-3) is a strategically symmetric halogenated heterocyclic scaffold engineered for cross-coupling reactions, ligand synthesis, and pharmaceutical intermediate development. Distinct from its 2,6-isomer, this molecule integrates a pyridine core with two bromine substituents at the C3 and C5 positions, creating a symmetric C₂ᵥ architecture where the bromines are meta to the ring nitrogen. This substitution pattern offers unique electronic properties compared to ortho-substituted analogs, making it particularly suitable for Pd-catalyzed cross-coupling (Suzuki, Stille, Negishi) where steric hindrance near the nitrogen needs to be minimized. The symmetric arrangement enables streamlined synthesis of C2-symmetric ligands, conjugated polymers, and bis-heterocyclic kinase inhibitors with specific binding geometries. While less activated for nucleophilic aromatic substitution (SNAr) than 2,6-dibromopyridine, the C3/C5-bromo handles provide excellent reactivity for metal-catalyzed functionalization, and the C2/C4/C6 positions remain available for electrophilic substitution or directed lithiation. Manufactured with purity ≥98% under controlled conditions, it supports drug discovery, materials science, and coordination chemistry programs requiring modular access to meta-symmetric pyridine architectures.

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Product Name
3,5-Dibromopyridine
CAS Number
625-92-3
Chinese Name
3,5-二溴吡啶
Synonyms
Pyridine, 3,5-dibromo-; 3,5-Dibromopyridine; 
Chinese Synonyms
3,5-二溴吡啶; 间二溴吡啶; 3,5-二溴氮苯; 对称二溴吡啶 (3,5-位)
Molecular Formula
C₅H₃Br₂N
Molecular Weight
236.89 g/mol
Purity
≥ 98% (GC/HPLC area normalization)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Dihalo heterocycles
Appearance
White to Off-white Crystalline Powder or Solid
Melting Point
~110-115°C (literature reference recommended)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen). Protect from strong bases and nucleophiles to avoid premature substitution.
Shelf Life
24 months under recommended storage conditions
Packaging
100mg/vial, 500mg/vial, 1g/bottle, 5g/bottle, or customized according to customer requirements
Applications
Ligand synthesis (meta-substituted terpyridines), conjugated polymer precursor, kinase inhibitor scaffold development, agrochemical intermediate, symmetric heterocycle construction, Pd-catalyzed cross-coupling reactions
Reactivity
Suitable for Suzuki coupling, Stille coupling, Negishi coupling, Sonogashira coupling, electrophilic aromatic substitution at C2/C4/C6, and directed lithiation
Special Note
✅ Meta-Symmetric Building Block—C3/C5 dibromo pattern offers distinct geometry vs. 2,6-isomer. Less sterically hindered for coupling near nitrogen. Isomer Differentiation—verify position via NMR. Part of our halogenated pyridine series.

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]]> https://wealsunbio.com/product/35-dibromopyridine/feed/ 0 2,6-Dibromopyridine https://wealsunbio.com/product/26-dibromopyridine/ https://wealsunbio.com/product/26-dibromopyridine/#respond Sun, 22 Feb 2026 12:57:56 +0000 https://wealsunbio.com/?post_type=product&p=23091 2,6-Dibromopyridine (CAS 626-05-1) is a strategically symmetric halogenated heterocyclic scaffold engineered for cross-coupling reactions, ligand synthesis, and pharmaceutical intermediate development. This molecule integrates a pyridine core—a nitrogen-containing six-membered aromatic ring—with two bromine substituents at the C2 and C6 positions, creating a symmetric C₂ᵥ architecture. The dual bromine handles are activated by the adjacent ring nitrogen, enabling efficient sequential or simultaneous Pd-catalyzed cross-coupling (Suzuki, Stille, Negishi, Sonogashira) to introduce diverse aryl, alkyl, or heteroaryl groups. The symmetric substitution pattern makes it a privileged precursor for constructing terpyridine ligands, conjugated polymers, and bis-heterocyclic kinase inhibitors where precise spatial arrangement of binding motifs is critical. Compared to mono-brominated or asymmetrically substituted pyridines, 2,6-dibromopyridine offers streamlined synthetic routes to C2-symmetric structures and enhanced binding affinity through chelation effects. Manufactured with purity ≥98% under controlled conditions, it supports drug discovery, materials science, and coordination chemistry programs requiring modular access to symmetrically functionalized pyridine architectures.

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Product Name
2,6-Dibromopyridine
CAS Number
626-05-1
Chinese Name
2,6-二溴吡啶
Synonyms
Pyridine, 2,6-dibromo-; 2,6-Dibromopyridine; C₅H₃Br₂N heterocycle; DBP
Chinese Synonyms
2,6-二溴吡啶; 二溴吡啶; 2,6-二溴氮苯; 对称二溴吡啶
Molecular Formula
C₅H₃Br₂N
Molecular Weight
236.89 g/mol
Purity
≥ 98% (GC/HPLC area normalization)
Product Category
Pharmaceutical Intermediates / Pyridine Derivatives / Dihalo heterocycles
Appearance
White to Off-white to Beige Crystalline Powder
Melting Point
119-121°C (literature)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen). Protect from strong bases and nucleophiles to avoid premature substitution.
Shelf Life
24 months under recommended storage conditions
Packaging
100mg/vial, 500mg/vial, 1g/bottle, 5g/bottle, or customized according to customer requirements
Applications
Terpyridine ligand synthesis, conjugated polymer precursor, kinase inhibitor scaffold development, agrochemical intermediate, symmetric heterocycle construction, Pd-catalyzed cross-coupling reactions
Reactivity
Suitable for Suzuki coupling, Stille coupling, Negishi coupling, Sonogashira coupling, nucleophilic aromatic substitution (SNAr), and lithiation at C3/C5 positions
Special Note
✅ Symmetric Building Block—C2/C6 dibromo pattern enables streamlined synthesis of C2-symmetric structures. Dual activated sites for sequential functionalization. Part of our halogenated pyridine series.

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]]> https://wealsunbio.com/product/26-dibromopyridine/feed/ 0 Vanadyl acetylacetonate https://wealsunbio.com/product/vanadyl-acetylacetonate/ https://wealsunbio.com/product/vanadyl-acetylacetonate/#respond Sat, 24 Jan 2026 12:59:44 +0000 https://wealsunbio.com/?post_type=product&p=22351 Vanadyl acetylacetonate (CAS 3153-26-2), also known as bis(acetylacetonato)oxovanadium(IV) or VO(acac)₂, is a versatile vanadium(IV) coordination complex engineered for catalysis, materials science, and bioinorganic research applications. This molecule integrates a paramagnetic vanadyl core (VO²⁺) with two bidentate acetylacetonate (acac) ligands, creating a stable square-pyramidal geometry that balances reactivity with thermal stability. The labile oxo ligand and coordinatively unsaturated vanadium center enable efficient oxygen atom transfer, radical initiation, and Lewis acid catalysis, while the chelating acac ligands provide solubility in organic media and volatility suitable for vapor-phase deposition techniques. This intermediate is particularly valuable for constructing oxidation catalysts, chemical vapor deposition (CVD) precursors for vanadium oxide thin films, polymerization initiators, and model compounds for studying vanadium-dependent enzymes such as haloperoxidases and nitrogenases. Manufactured with purity ≥98% under controlled conditions, it supports research programs requiring reliable vanadium sources with well-defined coordination chemistry and tunable redox properties.

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Product Name
Vanadyl acetylacetonate
CAS Number
3153-26-2
Chinese Name
乙酰丙酮氧钒 (IV)
Synonyms
Bis(acetylacetonato)oxovanadium(IV); VO(acac)₂; Vanadyl(IV) acetylacetonate; Oxovanadium(IV) bis(acetylacetonate);
Chinese Synonyms
双 (乙酰丙酮) 氧钒; 氧钒 (IV) 乙酰丙酮; 乙酰丙酮钒酰; 
Molecular Formula
C₁₀H₁₄O₅V
Molecular Weight
265.16 g/mol
Purity
≥ 98% (elemental analysis/HPLC)
Product Category
Fine Chemicals / Coordination Compounds / Vanadium Precursors
Appearance
Blue to Blue-Green Crystalline Powder or Solid
Melting Point
~230-235°C (decomposition, literature reference recommended)
Magnetic Properties
Paramagnetic (d¹ configuration, S = 1/2); EPR-active
Solubility
Soluble in chloroform, dichloromethane, ethanol; sparingly soluble in water
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen or argon). Protect from strong oxidizing agents and bases to avoid oxidation to V(V) or ligand displacement.
Shelf Life
24 months under recommended storage conditions
Packaging
1g/bottle, 5g/bottle, 10g/bottle, 25g/bottle, or customized according to customer requirements (amber glass, sealed with PTFE liner)
Applications
Oxidation catalysis (alkene epoxidation, alcohol oxidation), CVD/ALD precursor for VO₂/V₂O₅ thin films, polymerization catalyst (olefin polymerization), bioinorganic model studies (vanadium enzymes), EPR spectroscopy standard, organic synthesis reagent
Reactivity
Suitable for oxygen atom transfer reactions, radical initiation, Lewis acid catalysis, ligand exchange, thermal decomposition to vanadium oxides, and redox cycling between V(IV)/V(V) states
Special Note
✅ Paramagnetic Vanadyl Complex—EPR-active d¹ system ideal for spectroscopic studies. Thermally Stable Volatile Precursor—suitable for vapor-phase deposition. Part of our transition metal coordination compound series.

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]]> https://wealsunbio.com/product/vanadyl-acetylacetonate/feed/ 0 tert-Butyl N-(3-aminopropyl)-N-methylcarbamate https://wealsunbio.com/product/tert-butyl-n-3-aminopropyl-n-methylcarbamate/ https://wealsunbio.com/product/tert-butyl-n-3-aminopropyl-n-methylcarbamate/#respond Sat, 24 Jan 2026 12:59:18 +0000 https://wealsunbio.com/?post_type=product&p=22350 tert-Butyl N-(3-aminopropyl)-N-methylcarbamate (CAS 150349-36-3) is a strategically protected aliphatic diamine engineered for peptide mimetic synthesis, linker development, and heterocyclic construction in medicinal chemistry. This molecule integrates a propylenediamine backbone—a flexible three-carbon spacer prevalent in bioactive molecules—with orthogonal functionalization: one nitrogen atom bears an acid-labile Boc (tert-butoxycarbonyl) protecting group and a methyl substituent, while the terminal nitrogen remains as a primary amine. This differential substitution pattern enables selective deprotection and sequential functionalization, allowing chemists to introduce distinct moieties at each nitrogen terminus with precise spacing control. Compared to its ethyl-linked analog (CAS 121492-06-6), the propyl spacer offers enhanced conformational flexibility and altered distance between pharmacophores, which is critical for optimizing binding affinity in receptor ligands. The methyl group modulates basicity and metabolic stability, while the Boc group ensures compatibility with base-sensitive reactions and facilitates purification. This intermediate is particularly valuable for constructing imidazolidines, piperazines, macrocyclic scaffolds, and antibody-drug conjugate (ADC) linkers where controlled nitrogen reactivity and chain length are critical. Manufactured with purity ≥98% under controlled conditions, it supports drug discovery programs requiring modular access to differentially protected aliphatic diamine architectures.

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Product Name
tert-Butyl N-(3-aminopropyl)-N-methylcarbamate
CAS Number
150349-36-3
Chinese Name
叔丁基 N-(3-氨基丙基)-N-甲基氨基甲酸酯
Synonyms
Boc-N-Methyl-1,3-diaminopropane; N-Boc-N’-methylpropylenediamine; C₉H₂₀N₂O₂ protected diamine; Boc-Me-Propyl-EDA
Chinese Synonyms
Boc-甲基 -1,3-二氨基丙烷; N-Boc-N’-甲基丙二胺; 叔丁基甲基氨基丙基氨基甲酸酯; 保护性二胺中间体
Molecular Formula
C₉H₂₀N₂O₂
Molecular Weight
188.27 g/mol
Purity
≥ 98% (GC/HPLC area normalization)
Product Category
Pharmaceutical Intermediates / Protected Amines / Aliphatic Diamines
Appearance
Colorless to Pale Yellow Liquid
Boiling Point
~250-260°C at 760 mmHg (estimated)
Density
~0.96 g/cm³ (estimated)
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed under inert atmosphere (nitrogen). Protect from strong acids to avoid premature Boc deprotection.
Shelf Life
18-24 months under recommended storage conditions
Packaging
100mg/vial, 500mg/vial, 1g/bottle, 5g/bottle, or customized according to customer requirements
Applications
Peptide mimetic synthesis, heterocyclic construction (imidazolidines/piperazines), drug-linker conjugate development (ADC linkers), macrocyclic scaffold synthesis, sequential functionalization of diamines
Reactivity
Suitable for selective Boc deprotection (TFA/HCl), free amine acylation/alkylation, reductive amination, heterocyclic cyclization, and orthogonal protection strategies
Special Note
✅ Differentially Protected Diamine—enables sequential N-functionalization. Propyl spacer offers enhanced flexibility vs. ethyl analogs (CAS 121492-06-6). Acid-Sensitive Boc—avoid strong acids during storage. Part of our protected amine building block series.

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