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Methyl nicotinate
Methyl nicotinate (CAS 93-60-7), also known as Methyl pyridine-3-carboxylate or Nicotinic acid methyl ester, is a high-purity pyridine carboxylate ester intermediate widely used in pharmaceutical synthesis, organic chemistry research, cosmetic formulation, agrochemical development, and fine chemical manufacturing. This compound features a methyl ester group at the 3-position of the pyridine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in ester hydrolysis, amidation, and nucleophilic substitution, it exhibits excellent reactivity in conversion to nicotinic acid derivatives, niacinamide synthesis, and heterocyclic functionalization pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, cosmetic ingredient production (as a rubefacient/skin conditioning agent), and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing pyridine-3-carboxylate scaffolds, vitamin B3 derivatives, cosmetic active ingredients, and specialty chemical precursors. As a reliable pyridine derivative intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.
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Product Name
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Methyl nicotinate
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CAS Number
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93-60-7
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Chinese Name
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烟酸甲酯
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Synonyms
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Methyl pyridine-3-carboxylate; Nicotinic acid methyl ester; 3-Pyridinecarboxylic acid methyl ester; Pyridine-3-carboxylic acid, methyl ester;
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Chinese Synonyms
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3-吡啶羧酸甲酯; 烟酸甲酯; 尼古丁酸甲酯; 吡啶-3-甲酸甲酯; 尼克酸甲酯
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Molecular Formula
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C₇H₇NO₂
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Molecular Weight
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137.14 g/mol
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Purity
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≥ 98% (GC/HPLC)
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Product Category
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Pharmaceutical Intermediates / Pyridine Derivatives / Nicotinate Esters
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Appearance
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White to Off-white Crystalline Powder or Solid
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Melting Point
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38-42°C (literature)
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Boiling Point
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~240-245°C at 760 mmHg (estimated)
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Density
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~1.18 g/cm³ (estimated)
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Storage Conditions
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Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and bases. Store sealed at 2-8°C for extended stability.
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Shelf Life
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24 months under recommended storage conditions
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Packaging
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100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
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Applications
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Pharmaceutical intermediates, organic synthesis, API manufacturing, cosmetic ingredient production (rubefacient), vitamin B3 derivative synthesis, ester hydrolysis to nicotinic acid, amidation to niacinamide, agrochemical intermediates, fine chemical production
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Reactivity
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Suitable for ester hydrolysis to acid, amidation to amide, nucleophilic substitution, electrophilic aromatic substitution, and pyridine ring functionalization
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