Pyrimidine-2,5-diamine

2,5-Diaminopyrimidine (CAS 22715-27-1), also known as Pyrimidine-2,5-diamine or 2,5-Diaminepyrimidine, is a high-purity diamino-substituted heterocyclic intermediate widely used in pharmaceutical synthesis, organic chemistry research, nucleoside chemistry, and fine chemical manufacturing. This compound features amino groups at both the 2– and 5-positions of the pyrimidine ring, making it a versatile building block for the development of complex organic molecules and active pharmaceutical ingredients (APIs). As a key intermediate in condensation reactions, heterocyclic synthesis, and functional group transformations, it exhibits excellent reactivity in cyclization reactions, amide coupling, electrophilic aromatic substitution, and nucleophilic displacement pathways. Our product is manufactured under strict quality control standards, ensuring a purity of ≥98%, making it ideal for pharmaceutical manufacturing, medicinal chemistry research, antiviral drug synthesis, antifolate drug development, and scale-up production. This compound is particularly valuable in the synthesis of pharmaceuticals containing diaminopyrimidine scaffolds, nucleoside analog precursors, heterocyclic kinase inhibitor intermediates, and specialty chemical precursors. As a reliable heterocyclic intermediate from our product line, it serves as an important precursor for constructing functionalized nitrogenous heterocyclic systems in drug discovery and fine chemical development programs.

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Product Name	2,5-Diaminopyrimidine
CAS Number	22715-27-1
Chinese Name	2,5-二氨基嘧啶
Synonyms	Pyrimidine-2,5-diamine; 2,5-Diaminepyrimidine; 2,5-Pyrimidinediamine; C₄H₆N₄ heterocycle; MFCD00129726
Chinese Synonyms	嘧啶-2,5-二胺; 2,5-二氨基-1,3-二氮杂苯; 2,5-二胺嘧啶; 二氨基嘧啶
Molecular Formula	C₄H₆N₄
Molecular Weight	110.12 g/mol
Purity	≥ 98% (HPLC/GC)
Product Category	Pharmaceutical Intermediates / Heterocyclic Compounds / Diaminopyrimidines
Appearance	White to Off-white Crystalline Powder or Solid
Melting Point	~200°C (decomposition, literature)
Storage Conditions	Store in a cool, dry, well-ventilated area away from light and moisture. Keep container tightly closed. Protect from strong oxidizing agents and acids. Store sealed at 2-8°C for extended stability.
Shelf Life	24 months under recommended storage conditions
Packaging	100g/bottle, 500g/bottle, 1kg/bottle, 5kg/drum, or customized according to customer requirements
Applications	Pharmaceutical intermediates, organic synthesis, API manufacturing, nucleoside synthesis, antiviral drug development, antifolate drug synthesis, heterocyclic chemistry, condensation reactions, agrochemical intermediates, fine chemical production
Reactivity	Suitable for cyclization reactions, amide bond formation, electrophilic aromatic substitution, nucleophilic substitution, condensation with carbonyl compounds, and amino group derivatization